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NIH career development grants (K series)

Need assistance with NIH career development grants?

NIH career development grants (K series) are intended to provide support for trainees and early to mid-career scientists as a path toward conducting their research independently and being competitive for major grant support. 

When applying for a K series grant, follow the most current NIH SF424 guidance, as well as any specific instructions in the funding opportunity announcement (FOA). Additionally, access Duke guidance on K awards to ensure compliance with NIH requirements, including minimum effort needed. 

Also review additional NIH proposal guidance:

Note: The FOA instructions always supersede the SF424 guidance.

Support for NIH proposal development

Included below are grant writing toolkits developed by the SOM Office of Research Development and the Office of Campus Research Development (OCRD). 

Templates and examples

See below for templates and examples for commonly required sections of career development grants. Consult the FOA for specific section requirements that apply to that funding mechanism.
NIH K grants toolkit
NIH K grants Human Subjects and Clinical Trials attachments
Mentored NIH K award toolkit

Access the mentored NIH K award toolkit for guidance and templates to write a mentored K Award proposal. This toolkit is more tailored for campus faculty interested in PhD scientist-focused mentored K Awards (e.g., K01, K25). It is revised annually to conform to any updates in the SF424 guidelines.

NIH K99 toolkit

Access the NIH K99 award toolkit for guidance and templates to write a K99/R00 proposal. It is revised annually to conform to any updates in the SF424 guidelines.

NIH K grant examples

Explore examples of common career development grant sections. Please note that the examples are from previously awarded applications and the exact requirements and formatting may have changed.

The NIH RePORTER tool can be used to find other investigators at Duke who have been awarded a similar mechanism and may be able to provide additional examples or advice.