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NIH research grants (R series)

Need assistance with NIH research grants?

NIH research grants (R series) are intended to develop, support, and expand upon research programs for early career through senior investigators.   

When applying for a R series grant, follow the most current NIH SF424 guidance, as well as any specific instructions in the funding opportunity announcement (FOA).  Note: The FOA instructions always supersede the SF424 or standard page limitation guidance.

Also review additional NIH proposal guidance:

Guidance on review and submission of the proposal is available within myRESEARCHpath. If you have questions (e.g., what documents transfer from SPS versus what is uploaded into grants.duke), contact your grants administrator.

Support for NIH proposal development

Included below are grant writing toolkits developed by the SOM Office of Research Development and the Office of Campus Research Development (OCRD). 

Templates and examples

See below for templates and examples for commonly required sections of research grants. Consult the FOA for specific section requirements that apply to that funding mechanism.
NIH R grants toolkit

Access the NIH R grant toolkit for guidance and templates to write a standard R grant (i.e., R01, R21, or R03). It is revised annually to conform to any updates in the SF424 guidelines.

NIH R01 with clinical trial toolkit
NIH R01 without clinical trial toolkit
NIH R21 with clinical trial toolkit
NIH R21 without clinical trial toolkit
NIH R grants Human Subjects and Clinical Trials attachments